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Zotepine is a potent 5-HT2A, 5-HT2C, histamine H1, α1-adrenergic, and dopamine D2 receptor antagonist with Kd values of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM, and 8 nM, respectively.
| Molecular Weight | 331.86 |
| Formula | C18H18ClNOS |
| CAS Number | 26615-21-4 |
| Form | Solid |
| Solubility (25°C) | DMSO: ≥20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Katja Komossa, et al. Zotepine versus other atypical antipsychotics for schizophrenia
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