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Zonisamide sodium salt is an antiepileptic compound. It is effective in various animal models of epilepsy and in humans with partial and systemic seizures. Zonisamide sodium also removes nitric oxide (NO).
| Molecular Weight | 234.21 |
| Formula | C8H7N2NaO3S |
| CAS Number | 68291-98-5 |
| Solubility (25°C) | Water: ≥5 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Deborah Raymond, et al. SGCE Myoclonus-Dystonia
[3] Jing Li, et al. Determination of zonisamide by a coated monolithic column
[4] Piotr Czapiński, et al. Mechanisms of action of antiepileptic drugs
| Related Carbonic Anhydrase Products |
|---|
| Benzthiazide
Benzthiazide is a thiazide diuretic, promoting water loss from the body. |
| Brinzolamide
Brinzolamide (Brinzolamide) is a potent and effective carbonic anhydrase-II inhibitor with an IC50 of 3.19 nM.In addition, Brinzolamide reduces intraocular aqueous humor production in the eye and may be used in studies related to glaucoma. |
| Ethoxzolamide
Ethoxzolamide is an inhibitor of the metalloenzyme carbonic anhydrase, which inhibits hCA I, hCA II, hCA IV, hCA VI and hCA VII with Ki of 25 nM, 8 nM, 93 nM, 43 nM and 0.8 nM, respectively. |
| Fluorometholone Acetate
Fluorometholone Acetate is a synthetic corticosteroid and a potent carbonic anhydrase (CA) inhibitor with IC50s of 2.18 μM for hCA-I and 17.5 μM for hCA-II. It has anti-inflammatory activity and may be used in studies related to steroid-responsive ocular inflammation. |
| Methazolamide
Methazolamide is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively. |
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