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Zongertinib

Cat. No. M55200

All AbMole products are for research use only, cannot be used for human consumption.

Zongertinib Structure
Synonym:

BI 1810631

Size Price Availability Quantity
1mg USD 90 In stock
5mg USD 180 In stock
10mg USD 270 In stock
25mg USD 420 In stock
50mg USD 660 In stock
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Quality Control & Documentation
Biological Activity

Zongertinib (BI 1810631) is a human HER2-selective tyrosine kinase inhibitor that covalently binds to both wild-type and mutated HER2 receptors, including exon 20 insertion mutations, whilst sparing EGFR signaling. Zongertinib has antitumor activity.

Chemical Information
Molecular Weight 535.6
Formula C29H29N9O2
CAS Number 2728667-27-2
Solubility (25°C) DMSO 27 mg/mL
Storage Powder -20°C
References

[1] John Heymach, et al. Clin Lung Cancer. A Phase I, Open-LabeI, Dose Confirmation, Escalation, and Expansion TriαI of BI-1810631 as Monotherapy in Pαtlent With Advanced or Metastatic Solid Tumors With HER2 Aberrations

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Keywords: Zongertinib, BI 1810631 supplier, EGFR/HER2, inhibitors, activators

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