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Zolimomab aritox

Cat. No. M24656

All AbMole products are for research use only, cannot be used for human consumption.

Zolimomab aritox Structure
Synonym:

H65-ricin A chain immunotoxin, H65-RTA

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Quality Control & Documentation
Biological Activity

Zolimomab aritox (H65-RTA) is an immunocoupling compound consisting of a ricin (RTA) chain, a ribosomal inhibitory protein, coupled to a monoclonal antibody (H65) against the pan-T-cell antigen CD5. Zolimomab aritox has anticancer activity and can be used in cutaneous T-cell lymphoma studies.

Chemical Information
CAS Number 141483-72-9
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] P J Henslee-Downey, et al. Transplantation. Combined in vitro and in vivo T lymphocyte depletion for the control of graft-versus-host disease following haploidentical marrow transplant

[2] T L Schwinghammer, et al. Clin Pharm. Pharmacologic prophylaxis of acute graft-versus-host disease after allogeneic marrow transplantation

[3] A H Kung, et al. Fundam Appl Toxicol. Toxicologic evaluations of an immunotoxin, H65-RTA

[4] F J Stafford, et al. J Rheumatol. A pilot study of anti-CD5 ricin A chain immunoconjugate in systemic lupus erythematosus

[5] No authors listed. Cancer Invest. XomaZyme-791 and XomaZyme-H65

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Keywords: Zolimomab aritox, H65-ricin A chain immunotoxin, H65-RTA supplier, inhibitors, activators

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