All AbMole products are for research use only, cannot be used for human consumption.
ZM241385 is a novel non-xanthine adenosine receptor antagonist with selectivity for the A2a receptor subtype. ZM-241385 significantly blunts the hypotensive effects of CCPA and NECA without altering the bradycardia induced by these agonists. It blocks the infarct size-reducing effects(cardioprotective effects) of this two distinct adenosine receptor agonists.
In vitro: ZM-241385 exhibits high potency for A2a receptor-mediated effects versus A1 receptor-mediated effects. A2AR agonist CGS21680 dramatically up-regulated A2AR mRNA; this response was reversed by concurrent exposure to ZM241385.
Redox Rep. 2022 Dec;27(1):270-278.
Caffeine reduces oxidative stress to protect against hyperoxia-induced lung injury via the adenosine A2A receptor/cAMP/PKA/Src/ERK1/2/p38MAPK pathway
ZM241385 purchased from AbMole
Molecules. 2022 May 6;27(9):2994.
Inosine and D-Mannose Secreted by Drug-Resistant Klebsiella pneumoniae Affect Viability of Lung Epithelial Cells
ZM241385 purchased from AbMole
| Molecular Weight | 337.34 |
| Formula | C16H15N7O2 |
| CAS Number | 139180-30-6 |
| Solubility (25°C) | DMSO 35 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Adenosine Receptor Products |
|---|
| SYN115
Tozadenant (SYN115) is a novel, selective adenosine A(2A) receptor antagonist. |
| CGS 21680 hydrochloride
CGS 21680 hydrochloride is an A2A adenosine receptor agonist with an Ki of 27 nM. |
| Istradefylline
Istradefylline (KW-6002) is a potent, selective and orally active adenosine A2A receptor (A2AR) antagonist with Ki of 2.2 nM. |
| CGS 21680
CGS 21680 is a selective adenosine receptor agonist for A2A and A3 with Ki of 15 ng/mL and 37 ng/mL, respectively. |
| Norisoboldine
Norisoboldine is an isoquinoline alkaloid which acts as an AhR agonist. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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