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ZL0580 is a structural analogue of ZL0590 that induces epigenetic suppression of HIV by selectively binding to the BRD4 domain of BD1. ZL0580 induces inhibition of HIV by inhibiting Tat transcriptional activation and transcriptional prolongation, as well as inducing inhibition of chromatin structures on an HIV promoter.
| Molecular Weight | 532.53 |
| Formula | C25H23F3N4O4S |
| CAS Number | 2377151-10-3 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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