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Zidesamtinib is a potent, selective, orally active and blood-brain barrier permeable inhibitor of multiple ROS1 fusion and resistance mutations, with IC50 values of 0.7 and 7.9 nM for wild-type ROS1 and ROS1 G2032R, respectively, and does not inhibit TRK.May be useful in studies related to non-small cell lung cancer and other solid tumors.
| Molecular Weight | 419.45 |
| Formula | C22H22FN7O |
| CAS Number | 2739829-00-4 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related ROS Kinase Products |
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| Pinealon
Pinealon is a 3-amino acid peptide and shows neuroprotective properties. |
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