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Ziconotide (SNX-111), a peptide, is a potent and selective block of N-type calcium channels antagonist. Ziconotide reduces synaptic transmission, and can be used for chronic pain research.
| Molecular Weight | 2639.13 |
| Formula | C102H172N36O32S7 |
| CAS Number | 107452-89-1 |
| Solubility (25°C) | Water |
| Storage | -20°C, protect from light, dry, sealed |
[1] No authors listed. Ziconotide
[2] Shuai Gao, et al. Nature. Structure of human Cav2.2 channel blocked by the painkiller ziconotide
[4] Christopher S. Wie, et al. Ziconotide
[5] Timothy Strigenz. J Pain Palliat Care Pharmacother. Ziconotide
| Related Calcium Channel Products |
|---|
| KB-R7943 mesylate
KB-R7943 mesylate is a potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0.7 mM). |
| Cilnidipine
Cilnidipine is a dual L- and N-type calcium channel blocker that displays antihypertensive, sympatholytic and neuroprotective activity. |
| Azelnidipine
Azelnidipine is a novel dihydropyridine derivative, a L-type calcium channel blocker, and an antihypertensive. Azelnidipine inhibits the intracellular calcium ion flow and lower blood pressure by selectively blocking L-type calcium channel on the membrane of vascular smooth muscle. Azelnidipine inhibits esophageal squamous cell carcinoma proliferation by targeting MEK1/2. Azelnidipine also has anti-inflammatory, antioxidant and neuroprotective effects. |
| Catharanthine
Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM |
| Cinepazide maleate
Cinepazide maleate is a maleate salt form of cinepazide which is a vasodilator. |
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