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Zanamivir

Cat. No. M2072

All AbMole products are for research use only, cannot be used for human consumption.

Zanamivir Structure
Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
5mg USD 30 In stock
10mg USD 50 In stock
50mg USD 100 In stock
100mg USD 160 In stock
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Quality Control & Documentation
Biological Activity

Zanamivir (trade name Relenza) is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A virus and influenza B virus. Zanamivir works by binding to the active site of the neuraminidase protein, rendering the influenza virus unable to escape its host cell and infect others. Zanamivir is also an inhibitor of influenza virus replication in vitro and in vivo. In clinical trials it was found that zanamivir was able to reduce the time to symptom resolution by 1.5 days if therapy was started within 48 hours of the onset of symptoms. The bioavailability of zanamivir is 2%. After inhalation, zanamivir is concentrated in the lungs and oropharynx, where up to 15% of the dose is absorbed and excreted in urine.

Chemical Information
Molecular Weight 332.31
Formula C12H20N4O7
CAS Number 139110-80-8
Solubility (25°C) Water 30 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Moscona A. N Engl J Med. Neuraminidase inhibitors for influenza.

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Keywords: Zanamivir supplier, Anti-infection, inhibitors, activators

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