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YL93

Cat. No. M41351

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YL93 Structure

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Quality Control & Documentation
Biological Activity

YL93 is a dual inhibitors of MDM2/4 with Ki values of 0.64 μM and 1.1 nM for MDM4 and MDM2, respectively.

Chemical Information
Molecular Weight 711.62
Formula C37H38Cl2F2N4O4
CAS Number 2771313-42-7
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Shiyan Zhang et al. J Med Chem. Structure-Based Discovery of MDM2/4 Dual Inhibitors that Exert Antitumor Activities against MDM4-Overexpressing Cancer Cells

Related Mdm2 Products
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NSC 66811

NSC 66811 is a potent MDM2 inhibitor with Ki value of 120 nM, which disrupts MDM2-p53 interaction and activates p53 function.

Nutlin-3a

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Nutlin-3b

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SL-01

SL-01 is a p53-Mdm2 interaction inhibitor with IC50 of 3.18 μM.

  Catalog
Abmole Inhibitor Catalog




Keywords: YL93 supplier, Mdm2, inhibitors, activators

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