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YL-0919

Cat. No. M9252

All AbMole products are for research use only, cannot be used for human consumption.

YL-0919 Structure
Synonym:

Hypidone hydrochloride

Size Price Availability Quantity
10mM*1mL in DMSO USD 90 In stock
2mg USD 50 In stock
5mg USD 75 In stock
10mg USD 95 In stock
25mg USD 145 In stock
50mg USD 230 In stock
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Quality Control & Documentation
Biological Activity

YL-0919 is a novel 5-HT1A receptor agonist and selective serotonin reuptake inhibitor. YL-0919 inhibits the uptake of 5-HT into rat cerebral cortical synaptosomes and human recombinant cells with IC50 values of 1.78±0.34 nM and 1.93±0.18 nM, respectively.

Chemical Information
Molecular Weight 334.84
Formula C18H23ClN2O2
CAS Number 1339058-04-6
Solubility (25°C) DMSO: ≥ 24 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Qin JJ, et al. Neurosci Lett. The role of activation of the 5-HT1A receptor and adenylate cyclase in the antidepressant-like effect of YL-0919, a dual 5-HT1A agonist and selective serotonin reuptake inhibitor.

[2] Chen HX, et al. PLoS One. Antidepressant-like activity of YL-0919: a novel combined selective serotonin reuptake inhibitor and 5-HT1A receptor agonist.

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Keywords: YL-0919, Hypidone hydrochloride supplier, 5-HT Receptor, inhibitors, activators

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