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WIN 64338 hydrochloride

Cat. No. M7488

All AbMole products are for research use only, cannot be used for human consumption.

WIN 64338 hydrochloride Structure

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Quality Control & Documentation
Biological Activity

WIN 64338 hydrochloride is a the first potent, non-peptide, competitive bradykinin B2 receptor antagonist. In organ bath studies, WIN 64338 inhibits [3H]-bradykinin binding on guinea pig trachea with nanomolar affinity but is not active in the rabbit aorta (the classical bradykinin B1 preparation).

Chemical Information
Molecular Weight 783.95
Formula C45H68ClN4OP.HCl
CAS Number 163727-74-0
Solubility (25°C) DMSO 58.8 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Borsch-Haubold, et al. J Biol Chem. Direct inhibition of cyclooxygenase-1 and -2 by the kinase inhibitors SB 203580 and PD 98059.

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Keywords: WIN 64338 hydrochloride supplier, inhibitors, activators

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