Free shipping on all orders over $ 500

WCK-4234 

Cat. No. M28890

All AbMole products are for research use only, cannot be used for human consumption.

WCK-4234  Structure

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

WCK-4234 is a potent β-lactamase inhibitor. WCK-4234 inhibits class A, C, and D β-lactamases activity. WCK-4234 lacks direct antibacterial activity. WCK-4234 potentiates imipenem and meropenem against Enterobacteriaceae with OXA-48/OXA-181 or KPC enzymes, or with combinations of impermeability and AmpC or ESBL activity. WCK-4234 distinctively overcomes resistance mediated by OXA-type carbapenemases.

Chemical Information
Molecular Weight 269.21
Formula C7H8N3NaO5S
CAS Number 1804915-68-1
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage -20°C, dry, sealed
References

[1] Kiran Patil, et al. Biomed Chromatogr. Simultaneous determination of novel β-lactamase inhibitor WCK 4234 and Meropenem in dog plasma by LC-MS/MS and its application to preclinical pharmacokinetic study

[2] Alejandro Iregui, et al. Antimicrob Agents Chemother. Activity of Meropenem with a Novel Broader-Spectrum β-Lactamase Inhibitor, WCK 4234, against Gram-Negative Pathogens Endemic to New York City

[3] Krisztina M Papp-Wallace, et al. J Med Chem. Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using β-Lactamase Inhibitors and β-Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234

[4] Shazad Mushtaq, et al. J Antimicrob Chemother. WCK 4234, a novel diazabicyclooctane potentiating carbapenems against Enterobacteriaceae, Pseudomonas and Acinetobacter with class A, C and D β-lactamases

Related Antibiotic Products
Kanamycin sulfate

Kanamycin sulfate is an aminoglycoside antibiotic that acts as a bacteriostatic agent by binding to the bacterial 30S ribosome.

Marbofloxacin

Marbofloxacin is a potent antibiotic of the 3rd generation fluoroquinolone group which inhibiting bacterial DNA replication.

Linezolid

Linezolid (PNU-100766) is a synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis.

Daptomycin

Daptomycin is the first member of a new class of bactericidal antibiotics, the cyclic lipopeptides.

Sulfadimethoxine

Sulfadimethoxine (trade name Di-Methox, Albon) is a sulfonamide antibiotic.

  Catalog
Abmole Inhibitor Catalog




Keywords: WCK-4234  supplier, Antibiotic, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.