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TGFβ-IN-5 is a TGFβ inhibitor useful for the study of fibroproliferative diseases associated with TGF-β signaling.
| Molecular Weight | 312.37 |
| Formula | C20H16N4 |
| CAS Number | 259870-32-1 |
| Solubility (25°C) | DMSO 40 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related TGF-beta/Smad Products |
|---|
| Pirfenidone
Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone inhibits TGF-β bioactivity by affecting TGF-β2 mRNA expression and processing of pro-TGF-β in CCL-64 cells. Pirfenidone (AMR69) attenuates CCL2 and CCL12 production in fibrocyte cells. |
| Asiaticoside
Asiaticoside (Madecassol) is the active chemical component of the plant Centella asiatica. |
| Amygdalin
Laetrile is a glycoside initially isolated from the seeds of the tree Prunus dulcis, also known as bitter almonds. |
| Norcantharidin
Norcantharidin |
| Kartogenin
Kartogenin is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes. |
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