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WAY 181187 oxalate is a high affinity and selective 5-HT6 agonist (Ki = 2.2 nM). Displays 60-fold selectivity over other 5-HT and monoamine receptors. Increases firing rate of 5-HT neurons. Modifies sleep and wakefulness profiles following direct injections into the dorsal raphe nucleus, in vivo. Orally bioavailable.
| Molecular Weight | 470.91 |
| Formula | C15H13ClN4O2S2.C2H2O4 |
| CAS Number | 1883548-85-3 |
| Solubility (25°C) | DMSO 47.09 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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