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VU6015929 is a selective discoidin domain receptor 1/2 (DDR1/2) inhibitor with IC50s of 4.67 nM and 7.39 nM, respectively. VU6015929 potently blocks collagen-induced DDR1 activation and collagen-IV production.
Appl Microbiol Biotechnol. 2025 Feb 07;109(1):39.
Recombinant CD80 fusion protein combined with discoidin domain receptor 1 inhibitor for cancer treatment
VU6015929 purchased from AbMole
| Molecular Weight | 485.43 |
| Formula | C24H19F4N5O2 |
| CAS Number | 2442597-56-8 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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