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VU6012962 

Cat. No. M29504

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VU6012962  Structure

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Quality Control & Documentation
Biological Activity

VU6012962 is an orally bioavailable and CNS-penetrant metabotropic glutamate receptor 7 negative allosteric modulator (mGlu7 NAM) with an IC50 of 347 nM.

Chemical Information
Molecular Weight 448.4
Formula C21H19F3N4O4
CAS Number 2313526-86-0
Form Solid
Solubility (25°C) DMSO 125 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Carson W Reed, et al. J Med Chem. Discovery of an Orally Bioavailable and Central Nervous System (CNS) Penetrant mGlu7 Negative Allosteric Modulator (NAM) in Vivo Tool Compound: N-(2-(1 H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)-4-(cyclopropylmethoxy)-3-methoxybenzamide 䲧瘀Ỵ瘁㧀痿

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  Catalog
Abmole Inhibitor Catalog




Keywords: VU6012962  supplier, GluR, inhibitors, activators

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