Free shipping on all orders over $ 500

VU0410425 

Cat. No. M28203

All AbMole products are for research use only, cannot be used for human consumption.

VU0410425  Structure

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

VU0410425 is an mGlu1 negative allosteric modulator. VU0410425 exhibits potent inhibitory activity for rat mGlu1 with an IC50 value of 140 nM. VU0410425 can be used for the research of central nervous system disorders.

Chemical Information
Molecular Weight 369.8
Formula C19H16ClN3O3
CAS Number 1341167-72-3
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Hyekyung P Cho, et al. ACS Chem Neurosci. A novel class of succinimide-derived negative allosteric modulators of metabotropic glutamate receptor subtype 1 provides insight into a disconnect in activity between the rat and human receptors

Related GluR Products
AZD6765

AZD6765 is an NMDA receptor antagonist.

LY404039

LY404039 is a potent, selective and orally active agonist of recombinant human mGlu2, mGlu3 receptors with Ki of 149 nM, 92 nM respectively.

Felbamate

Felbamate(Felbatol) is an anticonvulsant compound used in epilepsy research.

CTEP

CTEP (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold selectivity over other mGlu receptors.

VU 0361737

VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively.

  Catalog
Abmole Inhibitor Catalog




Keywords: VU0410425  supplier, GluR, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.