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VU-0155069 is a potent and selective phospholipase D1 (PLD1) inhibitor with IC50 values of 46 and 933 nM for PLD1 and PLD2, respectively. VU0155069 inhibits migration of human and mouse breast cancer cell lines in transwell assays. VU0155069 significantly decreases invasive migration in breast cancer cell lines (MDA-231, 4T1 and PMT).
| Molecular Weight | 462.97 |
| Formula | C26H27ClN4O2 |
| CAS Number | 1130067-06-9 |
| Solubility (25°C) | DMSO: ≥ 20 mg/mL Ethanol: ≥ 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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