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VU 0155041 sodium salt

Cat. No. M7468

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VU 0155041 sodium salt Structure

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Quality Control & Documentation
Biological Activity

VU 0155041 sodium salt is a potent, positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50 = 798 and 693 nM at human and rat mGlu4 receptors respectively). Active in in vivo models of Parkinson's disease following i.c.v. administration.

Chemical Information
Molecular Weight 338.16
Formula C14H14Cl2NNaO3
CAS Number 1259372-69-4
Solubility (25°C) Water 8.45 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] He, et al. J Pharmacol Exp Ther. A role for tryptase in the activation of human mast cells: modulation of histamine release by tryptase and inhibitors of tryptase.

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