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Vipadenant

Cat. No. M10191

All AbMole products are for research use only, cannot be used for human consumption.

Vipadenant Structure
Synonym:

BIIB014; CEB-4520

Size Price Availability Quantity
1mg USD 36 In stock
5mg USD 80 In stock
10mg USD 124 In stock
25mg USD 224 In stock
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Quality Control & Documentation
Biological Activity

Vipadenant, also known as BIIB014, CEB-4520, is a potent, selective and orally available adenosine A2A receptor antagonist with Ki of 1.3 nM. Vipadenant is less potent for A1 with Ki of 69 nM. Vipadenant demonstrates strong oral activity in commonly used models of Parkinson's disease.

Product Citations
Chemical Information
Molecular Weight 321.34
Formula C16H15N7O
CAS Number 442908-10-3
Solubility (25°C) DMSO 30 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] N Jones, et al. Brain Res Bull. A2A receptor antagonists do not induce dyskinesias in drug-naive or L-dopa sensitized rats

[2] Brian C Shook, et al. ACS Chem Neurosci. Adenosine A(2A) Receptor Antagonists and Parkinson's Disease

[3] Annalisa Pinna. Expert Opin Investig Drugs. Novel investigational adenosine A2A receptor antagonists for Parkinson's disease

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Keywords: Vipadenant, BIIB014; CEB-4520 supplier, Adenosine Receptor, inhibitors, activators

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