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Vigabatrin hydrochloride

Cat. No. M14224

All AbMole products are for research use only, cannot be used for human consumption.

Vigabatrin hydrochloride Structure
Synonym:

γ-Vinyl-GABA hydrochloride

Size Price Availability
5mg USD 50 Out of stock
10mg USD 80 Out of stock
50mg USD 320 Out of stock
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Quality Control & Documentation
Biological Activity

Vigabatrin hydrochloride (γ-Vinyl-GABA hydrochloride), a inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. Vigabatrin hydrochloride is an antiepileptic agent, which acts by increasing GABA levels in the brain by inhibiting the catabolism of GABA by GABA transaminase.

Chemical Information
Molecular Weight 165.62
CAS Number 1391054-02-6
Solubility (25°C) Water 33.33 mg/mL
DMSO 27.5 mg/mL
Storage 2-8°C, sealed
References

[1] Pavel Klein, et al. Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?

[2] Muhamad Y Elrashidi, et al. Emerging drugs for the treatment of tobacco dependence: 2014 update

[3] Ze-Jun Wang, et al. A substituted anilino enaminone acts as a novel positive allosteric modulator of GABA(A) receptors in the mouse brain

[4] A Padovan Lang, et al. Experimental anxiety and antiepileptics: the effects of valproate and vigabatrin in the mirrored chamber test

[5] M Bialer, et al. Progress report on new antiepileptic drugs: a summary of the fourth Eilat conference (EILAT IV)

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Keywords: Vigabatrin hydrochloride, γ-Vinyl-GABA hydrochloride supplier, GABA Receptor, inhibitors, activators

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