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Vidutolimod

Cat. No. M43821

All AbMole products are for research use only, cannot be used for human consumption.

Vidutolimod Structure
Synonym:

CMP-001

Price and Availability

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Quality Control & Documentation
Biological Activity

Vidutolimod is a CpG-A oligodeoxynucleotide. Vidutolimod is a Toll-like receptor 9 (TLR9) agonist, which activates plasmacytoid dendritic cells (pDCs) and triggers interferon alpha (IFNα) release, leading to a cascade of anti-tumor immune effects.

Chemical Information
Molecular Weight 9612.23
CAS Number 147063-80-7
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ofer Margalit, et al. Clin Colorectal Cancer. Combination Treatment of Intratumoral Vidutolimod, Radiosurgery, Nivolumab, and Ipilimumab for Microsatellite Stable Colorectal Carcinoma With Liver Metastases

[2] Ryan J Sullivan. Cancer Discov. For Whom the Bell Tolls? A Toll-Like Receptor 9 Agonist's Journey from Vaccine Adjuvant to Promising Agent in Anti-PD-1-Resistant Melanoma

[3] Shakoora A Sabree, et al. Vaccines (Basel). Monocytes Exposed to Immune Complexes Reduce pDC Type 1 Interferon Response to Vidutolimod

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Keywords: Vidutolimod, CMP-001 supplier, TLR, inhibitors, activators

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