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Verinurad

Cat. No. M9351

All AbMole products are for research use only, cannot be used for human consumption.

Verinurad Structure
Synonym:

RDEA3170

Size Price Availability Quantity
10mM*1mL in DMSO USD 88 In stock
5mg USD 80 In stock
10mg USD 110 In stock
25mg USD 200 In stock
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Biological Activity

Verinurad, also known as RDEA3170, is an organic anion transporter URAT1 inhibitor with an IC50 of 25 nM.

Chemical Information
Molecular Weight 348.42
Formula C20H16N2O2S
CAS Number 1352792-74-5
Solubility (25°C) DMSO ≥ 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Tan PK, et al. Sci Rep. Discovery and characterization of verinurad, a potent and specific inhibitor of URAT1 for the treatment of hyperuricemia and gout.

[2] Diaz-Torne C, et al. Curr Opin Rheumatol. New medications in development for the treatment of hyperuricemia of gout.

Related URAT1 Products
Lesinurad

Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively.
Dotinurad

Dotinurad is a potent selective urate reabsorption inhibitor. Dotinurad inhibits Urate Transporter 1 (URAT1), IC50 value is 37.2 nM. Dotinurad is used as a uric acid-enhancing excretor.
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Abmole Inhibitor Catalog




Keywords: Verinurad, RDEA3170 supplier, URAT1, inhibitors, activators

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