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Vedolizumab

Cat. No. M1618

All AbMole products are for research use only, cannot be used for human consumption.

Vedolizumab Structure
Synonym:

MLN-02; LDP-02; MLN0002

Size Price Availability Quantity
5mg USD 800 In stock
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Quality Control & Documentation
Biological Activity

Vedolizumab is a humanized monoclonal antibody that specifically antagonizes Integrin (α4β7) and inhibits the binding of α4β7 to the intestinal mucosal cell adhesion molecule MADCAM-1. Vedolizumab is indicated for humanized mice.

Chemical Information
Molecular Weight 146834.53
Formula C6528H10072N1732O2042S42
CAS Number 943609-66-3
Storage -80°C for long term
References

[1] Fedyk ER, et al. Inflamm Bowel Dis. Exclusive antagonism of the α4 β7 integrin by vedolizumab confirms the gut-selectivity of this pathway in primates.

[2] Soler D, et al. J Pharmacol Exp Ther. The binding specificity and selective antagonism of vedolizumab, an anti-alpha4beta7 integrin therapeutic antibody in development for inflammatory bowel diseases.

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Keywords: Vedolizumab, MLN-02; LDP-02; MLN0002 supplier, Integrin, inhibitors, activators

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