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Vapendavir

Cat. No. M30094

All AbMole products are for research use only, cannot be used for human consumption.

Vapendavir Structure
Synonym:

BTA798

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Quality Control & Documentation
Biological Activity

Vapendavir (BTA798) is a potent enteroviral capsid binder (CB). Vapendavir (BTA798) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains.

Chemical Information
Molecular Weight 382.46
Formula C21H26N4O3
CAS Number 439085-51-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Kristina Lanko, et al. Antiviral Res. Comparative analysis of the molecular mechanism of resistance to vapendavir across a panel of picornavirus species

[2] Jiri Wald, et al. Proc Natl Acad Sci U S A. Cryo-EM structure of pleconaril-resistant rhinovirus-B5 complexed to the antiviral OBR-5-340 reveals unexpected binding site

[3] Aloys Tijsma, et al. Antimicrob Agents Chemother. The capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication

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Keywords: Vapendavir, BTA798 supplier, Anti-infection, inhibitors, activators

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