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Valerenic acid

Cat. No. M29976

All AbMole products are for research use only, cannot be used for human consumption.

Valerenic acid Structure
Synonym:

(-)-Valerenic Acid

Size Price Availability Quantity
1mg USD 110 In stock
5mg USD 290 In stock
10mg USD 460 In stock
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Quality Control & Documentation
Biological Activity

Valerenic acid ((-)-Valerenic Acid), a sesquiterpenoid, is an orally active positive allosteric modulator of GABAA receptors. Valerenic acid is also a partial agonist of the 5-HT5a receptor. Valerenic acid mediates anxiolytic activity via GABAA receptors containing the β3 subunit. Valerenic acid also exhibits potent antioxidant properties.

Chemical Information
Molecular Weight 234.33
Formula C15H22O2
CAS Number 3569-10-6
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jun Takahashi, et al. ACS Omega. Valerenic Acid Promotes Adipocyte Differentiation, Adiponectin Production, and Glucose Uptake via Its PPARγ Ligand Activity

[2] Mengya Zhao, et al. Biotechnol Lett. Biosynthesis of valerenic acid by engineered Saccharomyces cerevisiae

[3] Alfredo Rodríguez-Cruz, et al. IBRO Rep. "Effect of valerenic acid on neuroinflammation in a MPTP-induced mouse model of Parkinson's disease"

[4] Ekrem-Murat Gonulalan, et al. Saudi Pharm J. The roles of valerenic acid on BDNF expression in the SH-SY5Y cell

[5] No authors listed. Valerian

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Keywords: Valerenic acid, (-)-Valerenic Acid supplier, GABA Receptor, inhibitors, activators

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