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V-11-0711 

Cat. No. M28407

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V-11-0711  Structure

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Quality Control & Documentation
Biological Activity

V-11-0711 is a potent and selective choline kinase alpha (ChoKα) inhibitor with an IC50 of 20 nM. V-11-0711 causes a reversible growth arrest in HeLa cells.

Chemical Information
Molecular Weight 421.57
Formula C27H35NO3
CAS Number 1428339-47-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Katharina Koch, et al. Oncotarget. Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells

[2] Noriko Mori, et al. NMR Biomed. Choline kinase-α protein and phosphatidylcholine but not phosphocholine are required for breast cancer cell survival

[3] S C Falcon, et al. Oncogenesis. A non-catalytic role of choline kinase alpha is important in promoting cancer cell survival

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Abmole Inhibitor Catalog




Keywords: V-11-0711  supplier, inhibitors, activators

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