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UZH2 is a potent and selective METTL3 inhibitor with an IC50 value of 5 nM.
| Molecular Weight | 513.63 |
| Formula | C27H37F2N7O |
| CAS Number | 2756566-45-5 |
| Form | Solid |
| Solubility (25°C) | DMSO 50 mg/mL (ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related METTL3 Products |
|---|
| STM2457
STM2457 is a first-in-class, potent and specific, orally active METTL3 inhibitor with an IC50 of 16.9 nM and excellent in vivo activity. |
| S-Adenosylhomocysteine
S-Adenosylhomocysteine, an intermediate in the synthesis of cysteine and adenosine, is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 µM. |
| STC-15
STC-15 is a METTL3 inhibitor used in the study of proliferative diseases such as cancer and autoimmune diseases. |
| STM2120
STM2120 is a METTL3-METTL14 inhibitor with an IC50 of 64.5 μM. |
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