Free shipping on all orders over $ 500

UPGL00004

Cat. No. M20645

All AbMole products are for research use only, cannot be used for human consumption.

UPGL00004 Structure
Size Price Availability Quantity
10mg USD 160 In stock
25mg USD 310 In stock
50mg USD 530 In stock
100mg USD 900 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

UPGL00004 is a potent glutaminase C (GAC) inhibitor with an IC50 of 29 nM, showing high selectivity for GAC over GLS2.

Chemical Information
Molecular Weight 534.66
Formula C25H26N8O2S2
CAS Number 1890169-95-5
Solubility (25°C) DMSO 25 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Luqman Shah, et al. RSC Adv. Recombinant l-glutaminase obtained from Geobacillus thermodenitrificans DSM-465: characterization and in silico elucidation of conserved structural domains

[2] Qingqiu Huang, et al. J Biol Chem. Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism

Related GluR Products
AZD6765

AZD6765 is an NMDA receptor antagonist.

LY404039

LY404039 is a potent, selective and orally active agonist of recombinant human mGlu2, mGlu3 receptors with Ki of 149 nM, 92 nM respectively.

Felbamate

Felbamate(Felbatol) is an anticonvulsant compound used in epilepsy research.

CTEP

CTEP (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold selectivity over other mGlu receptors.

VU 0361737

VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively.

  Catalog
Abmole Inhibitor Catalog




Keywords: UPGL00004 supplier, GluR, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.