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UNC 926 hydrochloride is a methyl-lysine (Kme) reader domain inhibitor; binds to the MBT domain of the L3MBTL1 protein (Kd = 3.9 μM). Selectively inhibits the L3MBTL13XMBT-H4K20me1 interaction in a peptide pull down assay.
| Molecular Weight | 373.72 |
| Formula | C16H21BrN2O.HCl |
| CAS Number | 1184136-10-4 |
| Solubility (25°C) | Water 37.37 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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