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UK-432097 

Cat. No. M30019

All AbMole products are for research use only, cannot be used for human consumption.

UK-432097  Structure

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Quality Control & Documentation
Biological Activity

UK-432097 is a highly potent and selective A2AAR agonist with a pKi of 8.4 for human A2AAR. UK-432097 has anti-inflammatory and anti-aggregatory properties. UK-432097 has the potential for COPD (Chronic Obstructive Pulmonary Disease) research.

Chemical Information
Molecular Weight 777.87
Formula C40H47N11O6
CAS Number 380221-63-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Min Cui, et al. IUCrJ. Crystal structure of a constitutive active mutant of adenosine A2A receptor

[2] Magdalena Boncler, et al. Vascul Pharmacol. Adenosine receptor agonists deepen the inhibition of platelet aggregation by P2Y12 antagonists

[3] Angel Guerrero. Curr Med Chem. A2A Adenosine Receptor Agonists and their Potential Therapeutic Applications. An Update

[4] Simon Mantell, et al. Expert Rev Clin Pharmacol. Design and application of locally delivered agonists of the adenosine A(2A) receptor

[5] Fei Xu, et al. Science. Structure of an agonist-bound human A2A adenosine receptor

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Keywords: UK-432097  supplier, Adenosine Receptor, inhibitors, activators

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