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UK-370106 is a potent and highly selective MMP-3 (IC50 of 23 nM) and MMP-12 (IC50 of 42 nM) inhibitor with >1200-fold higher potency than MMP-1, MMP-2, MMP-9, and MMP-14, and about 100-fold than MMP-13 and MMP-8.
| Molecular Weight | 572.73 |
| Formula | C35H44N2O5 |
| CAS Number | 230961-21-4 |
| Form | Solid |
| Solubility (25°C) | DMSO 120 mg/mL |
| Storage | Powder -20°C |
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