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U18666A is an intra-cellular cholesterol transport inhibitor. U18666A inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus.
Inhibitor of cholesterol synthesis (inhibits desmosterol Δ24-reductase). Weak inhibitor of hedgehog (hh) signaling.
| Molecular Weight | 424.06 |
| Formula | C25H41NO2·HCl |
| CAS Number | 3039-71-2 |
| Solubility (25°C) | DMSO 15 mg/mL Water 4.5 mg/mL |
| Storage | -20°C, sealed |
[1] Hongtao Shen, et al. BRD2 regulation of sigma-2 receptor upon cholesterol deprivation
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