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Tutuilamide A 

Cat. No. M29801

All AbMole products are for research use only, cannot be used for human consumption.

Tutuilamide A  Structure

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Quality Control & Documentation
Biological Activity

Tutuilamide A is a potent porcine pancreatic elastase (PPE) inhibitor, with an IC50 of 1.2 nM. Tutuilamide A also inhibits human neutrophil elastase (HNE; IC50=0.73 nM) and kallikrein 7 (KLK7; IC50=5.0 nM).

Chemical Information
Molecular Weight 1021.59
Formula C51H69ClN8O12
CAS Number 2756129-42-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Qi-Yin Chen, et al. Bioorg Med Chem. Ahp-Cyclodepsipeptides as tunable inhibitors of human neutrophil elastase and kallikrein 7: Total synthesis of tutuilamide A, serine protease selectivity profile and comparison with lyngbyastatin 7

[2] Lena Keller, et al. ACS Chem Biol. Tutuilamides A-C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties

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  Catalog
Abmole Inhibitor Catalog




Keywords: Tutuilamide A  supplier, Elastase, inhibitors, activators

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