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TUG-1375

Cat. No. M11254

All AbMole products are for research use only, cannot be used for human consumption.

TUG-1375  Structure
Size Price Availability Quantity
1mg USD 135 In stock
5mg USD 335 In stock
10mg USD 540 In stock
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Quality Control & Documentation
Biological Activity

Tug-1375 is a free fatty acid receptor 2 (FFA2/GPR43) agonist with a pKi value of 6.69. TUG-1375 had no effect on FFA3, FFA4, PPARα, PPARγ, PPARδ, LXRα or LXRβ.

Chemical Information
Molecular Weight 442.92
Formula C22H19ClN2O4S
CAS Number 2247372-59-2
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Estela Lorza-Gil, et al. Sci Rep. FFA2-, but not FFA3-agonists inhibit GSIS of human pseudoislets: a comparative study with mouse islets and rat INS-1E cells

[2] Anders Hjgaard Hansen, et al. J Med Chem. Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties

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