Free shipping on all orders over $ 500

Tucotuzumab

Cat. No. M25216

All AbMole products are for research use only, cannot be used for human consumption.

Tucotuzumab Structure
Synonym:

Anti-EPCAM Recombinant Antibody huKS-IL2

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.

Quality Control & Documentation
Biological Activity

Tucotuzumab (Anti-EPCAM Recombinant Antibody) is a protein composed of an IgG1 monoclonal antibody specific for the human Epithelial Cell Adhesion Molecule (EpCAM) antigen, linked to two molecules of IL-2. Tucotuzumab is an immunosuppressant and antineoplastic agent.

Chemical Information
CAS Number 339986-90-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Shirin Eyvazi, et al. Curr Cancer Drug Targets. Antibody Based EpCAM Targeted Therapy of Cancer, Review and Update

[2] Jennifer A A Gubbels, et al. Cancer Immunol Immunother. Ab-IL2 fusion proteins mediate NK cell immune synapse formation by polarizing CD25 to the target cell-effector cell interface

[3] Erik E Johnson, et al. Clin Cancer Res. Radiofrequency ablation combined with KS-IL2 immunocytokine (EMD 273066) results in an enhanced antitumor effect against murine colon adenocarcinoma

Related IL Receptor/Related Products
Reslizumab

Reslizumab (Sch 55700) is a humanized monoclonal antibody targeting human interleukin 5 (IL-5) for the study of eosinophilic asthma. Reslizumab effectively blocks il-5 function. Reslizumab inhibited IL-5-dependent cell proliferation with an IC50 of about 91.1 pM.
Montelukast sodium

Montelukast sodium selectively antagonizes leukotriene D 4 (LTD4) by binding to it so that block the action of leukotriene D4 on the cysteinyl leukotriene receptor CysLT1.
VGX-1027

VGX-1027 is an orally active immunomodulator.
Diacerein

Diacerin is an inhibitor of pro-inflammatory cytokine Interleukin-1B (IL-1B) production, prescribed for osteoarthritis and chronic inflammatory arthritis.
SC144

SC144 is the first oral active GP130 (IL6-beta) inhibitor. SC144 binds gp130, induces gp130 phosphorylation (S782) and deglycosylation, eliminates Stat3 phosphorylation and nuclear translocation, and further inhibits downstream target gene expression. SC144 inhibited signal transduction induced by GP130 ligand. SC144 induces apoptosis of human ovarian cancer cells.
  Catalog
Abmole Inhibitor Catalog




Keywords: Tucotuzumab, Anti-EPCAM Recombinant Antibody huKS-IL2 supplier, IL Receptor/Related, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
Get to Know Us
Customer Support
Resources
Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.