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Trovafloxacin mesylate

Cat. No. M7436

All AbMole products are for research use only, cannot be used for human consumption.

Trovafloxacin mesylate Structure

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Quality Control & Documentation
Biological Activity

Trovafloxacin mesylate is a fluoroquinolone antibiotic. Inhibits bacterial DNA topoisomerase IV and DNA gyrase and forms a stable quinolone-DNA complex with these enzymes which reversibly inhibits DNA synthesis. Displays potent activity against gram-positive and gram-negative bacteria. Increases the production of mitochondrial NO in immortalized hepatocytes; also increases mitochondrial Ca2+. Inhibits Panx-1 (IC50 ~ 4μM).

Chemical Information
Molecular Weight 512.46
Formula C20H15F3N4O3.CH3SO3H
CAS Number 147059-75-4
Solubility (25°C) Water 25.62 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Waring and Beaver. Gen Pharmacol. Gliotoxin and related epipolythiodioxopiperazines.

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Keywords: Trovafloxacin mesylate supplier, inhibitors, activators

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