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Trospium chloride is a competitive muscarinic cholinergic receptor antagonist. Trospium chloride is a quaternary ammonium compound. Trospium chloride dosed 20 mg twice daily, is significantly superior to placebo in improving cystometric parameters, reducing urinary frequency, reducing incontinence episodes, and increasing urine volume per micturition. In active-controlled trials, trospium chloride was at least equivalent to immediate-release formulations of oxybutynin and tolterodine in efficacy and tolerability.
| Molecular Weight | 427.96 |
| Formula | C25H30NO3.Cl |
| CAS Number | 10405-02-4 |
| Solubility (25°C) | Water 90 mg/mL DMSO 30 mg/mL |
| Storage | 4°C, dry, sealed |
[2] Eric S Rovner. Drυgs. Trospium chloride in the management of overactive bladder
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