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Troleandomycin

Cat. No. M29794

All AbMole products are for research use only, cannot be used for human consumption.

Troleandomycin Structure
Synonym:

Triacetyloleandomycin

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Quality Control & Documentation
Biological Activity

Troleandomycin (Triacetyloleandomycin), a macrolide acrolide antibiotic, is a selective CYP3A inhibitor. Troleandomycin is an oral corticosteroid for asthma study.

Chemical Information
Molecular Weight 813.97
Formula C41H67NO15
CAS Number 2751-09-9
Form Solid
Solubility (25°C) DMSO 83.33 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] D J Evans, et al. Cochrane Database Syst Rev. Troleandomycin as an oral corticosteroid steroid sparing agent in stable asthma

[2] A Siracusa, et al. J Allergy Clin Immunol. Troleandomycin in the treatment of difficult asthma

[3] J P Miguet, et al. Ann Intern Med. Jaundice from troleandomycin and oral contraceptives

[4] D Warot, et al. Eur J Clin Pharmacol. Troleandomycin-triazolam interaction in healthy volunteers: pharmacokinetic and psychometric evaluation

[5] W F Ebling, et al. Eur J Drug Metab Pharmacokinet. Troleandomycin effects on methylprednisolone and methylprednisone interconversion and disposition in the rabbit

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Keywords: Troleandomycin, Triacetyloleandomycin supplier, Cytochrome P450 (e.g. CYP17), inhibitors, activators

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