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TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry.
Biosensors. 2023 Apr 3.
Chemiluminescence Biosensor for the Determination of Cardiac Troponin I (cTnI)
Tris(2-carboxyethyl)phosphine hydrochloride purchased from AbMole
| Molecular Weight | 286.65 |
| Formula | C9H15O6P·HCl |
| CAS Number | 51805-45-9 |
| Solubility (25°C) | 45 mg/mL in water (adjust pH with NaOH) DMSO 90 mg/mL |
| Storage | 2-8°C, protect from light, sealed |
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