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Trifluoperazine

Cat. No. M20668

All AbMole products are for research use only, cannot be used for human consumption.

Trifluoperazine Structure
Synonym:

NSC-17474, RP-7623, SKF-5019

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Quality Control & Documentation
Biological Activity

Trifluoperazine is an FDA-approved antipsychotic drug for schizophrenia. It is an inhibitor of calmodulin (CaM) and Dopamine D2 receptor with an IC50 value of 1.2 nM for D2 receptor.

Chemical Information
Molecular Weight 407.5
Formula C21H24F3N3S
CAS Number 117-89-5
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Luana E Piccini, et al. Arch Virol. Inhibition of dengue virus infection by trifluoperazine

[2] Zizi Jing, et al. Tohoku J Exp Med. Trifluoperazine Synergistically Potentiates Bortezomib-Induced Anti-Cancer Effect in Multiple Myeloma via Inhibiting P38 MAPK/NUPR1

[3] Magdolna Tardy, et al. Cochrane Database Syst Rev. Trifluoperazine versus low-potency first-generation antipsychotic drugs for schizophrenia

[4] Kai Koch, et al. Cochrane Database Syst Rev. Trifluoperazine versus placebo for schizophrenia

[5] L O Marques, et al. Cochrane Database Syst Rev. Trifluoperazine for schizophrenia

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  Catalog
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Keywords: Trifluoperazine, NSC-17474, RP-7623, SKF-5019 supplier, Dopamine Receptor, inhibitors, activators

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