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Triclabendazole is a benzimidazole, it binds to tubulin impairing intracellular transport mechanisms and interferes with protein synthesis. Triclabendazole induces gasdermin E (GSDME)-dependent pyroptosis by caspase-3 activation. Triclabendazole can be used for the research of fasciola hepatica.
| Molecular Weight | 359.66 |
| Formula | C14H9Cl3N2OS |
| CAS Number | 68786-66-3 |
| Form | Solid |
| Solubility (25°C) | DMSO 80 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] No authors listed. Triclabendazole
[3] Preetam Gandhi, et al. Triclabendazole in the treatment of human fascioliasis: a review
[4] No authors listed. Triclabendazole
[5] G P Brennan, et al. Understanding triclabendazole resistance
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