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Triazavirin

Cat. No. M9650

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Triazavirin Structure
Synonym:

Riamilovir sodium dihydrate

Size Price Availability Quantity
5mg USD 50 In stock
10mg USD 80 In stock
50mg USD 250 In stock
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Quality Control & Documentation
Biological Activity

Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent, works by inhibiting the synthesis of viral RNA and DNA and replication of genomic fragments. Triazavirin is shown active in inhibition of the tick-borne encephalitis virus reproduction (strain Sofiin) by accumulation in the SKEV cell culture.

In high doses (200-400 mg/kg) Triazavirin moderately protects the infected animals. A significant increase of the animal lifespan in the test groups (from 4.1 to 4.8 days) and a statistically valid decrease of the virus accumulation in the target organ are observed.

Product Citations
Chemical Information
Molecular Weight 286.20
Formula C5H7N6NaO5S
CAS Number 928659-17-0
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ksenia V Kozhikhova, et al. Pharm Dev Technol. Preparation of chitosan-coated liposomes as a novel carrier system for the antiviral drv g Triazavirin

[2] S Ya Loginova, et al. Antibiot Khimioter. Investigation of Therapeutic Efficacy of Triazavirin Against Experimental Forest-Spring Encephalitis on Albino Mice

[3] S Ia Loginova, et al. Antibiot Khimioter. Investigation of Triazavirin antiviral activity against tick-borne encephalitis pathogen in cell culture

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Keywords: Triazavirin, Riamilovir sodium dihydrate supplier, DNA/RNA Synthesis, inhibitors, activators

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