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Tregalizumab

Cat. No. M24578

All AbMole products are for research use only, cannot be used for human consumption.

Tregalizumab Structure
Synonym:

BT-061

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Quality Control & Documentation
Biological Activity

Tregalizumab is a humanized anti-human CD4 monoclonal antibody (IgG1 type) that selectively activates the suppressive properties of regulatory T cells (Tregs) in vitro. Tregalizumab can be used in the research of autoimmune diseases (resulting from insufficient Treg activity) and allergies.

Chemical Information
CAS Number 1207446-68-1
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Andreas Kerschbaumer, et al. Ann Rheum Dis. Efficacy of pharmacological treatment in rheumatoid arthritis: a systematic literature research informing the 2019 update of the EULAR recommendations for management of rheumatoid arthritis

[2] Martin König, et al. Front Immunol. Tregalizumab - A Monoclonal Antibody to Target Regulatory T Cells

[3] Bianca Helling, et al. Immunol Cell Biol. A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway

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Keywords: Tregalizumab, BT-061 supplier, inhibitors, activators

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