All AbMole products are for research use only, cannot be used for human consumption.
-HCl.gif)
Tranylcypromine HCl is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively. Tranylcypromine hydrochlorid (50 μM-5 mM; 1 h or 12-14 h) inhibits histone and nucleosomal demethylation.
Tranylcypromine hydrochlorid (3 mg/kg; i.p. once daily for 3 days) decreases LPS-mediated microglial activation and proinflammatory cytokine COX-2 and IL-6 levels in wild-type mice. Tranylcypromine hydrochlorid (3 mg/kg; i.p. once daily for 7 days) down-regulates Aβ-mediate microglial activation in 5xFAD mice.
| Molecular Weight | 169.65 |
| Formula | C9H12ClN |
| CAS Number | 1986-47-6 |
| Solubility (25°C) | Water 60 mg/mL DMSO 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Monoamine Oxidase Products |
|---|
| Safinamide Mesylate
Safinamide is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor. |
| Clorgyline hydrochloride
Clorgiline is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A). |
| Guanethidine Hemisulfate
Guanethidine Hemisulfate is an antihypertensive compound that reduces the release of catecholamines such as norepinephrine. |
| Moclobemide
Moclobemide is a MAO-A (5-HT) inhibitor with IC50 of 6.1 μM. |
| Nialamide
Nialamide is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class used as an antidepressant and anxiolytic. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
