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trans-Aconitic acid

Cat. No. M11219

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trans-Aconitic acid  Structure
Synonym:

TAA

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Quality Control & Documentation
Biological Activity

Trans-Aconitic acid is present in normal human urine and may be abundantly present in Reye syndrome and organic aciduria. trans-Aconitic acid is a substrate of trans-pyruvate 2-methyltransferase.

Chemical Information
Molecular Weight 174.11
Formula C6H6O6
CAS Number 4023-65-8
Solubility (25°C) DMSO ≥ 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Arisa Takiguchi, et al. J Biosci Bioeng. Constitutive production of aconitate isomerase by Pseudomonas sp. WU-0701 in relation to trans-aconitic acid assimilation

[2] Tiara da Silva Coelho Bortolo, et al. Plant Physiol Biochem. Trans-aconitic acid inhibits the growth and photosynthesis of Glycine max

[3] Diego Pinto de Oliveira, et al. Biomed Pharmacother. Esterification of trans-aconitic acid improves its anti-inflammatory activity in LPS-induced acute arthritis

[4] William Piang-Siong, et al. Food Chem. Contribution of trans-aconitic acid to DPPH scavenging ability in different media

[5] R Burau, et al. Science. Trans-Aconitic Acid in Range Grasses in Early Spring

Related Metabolite/Endogenous Metabolite Products
2'-Deoxyinosine

2′-Deoxyinosine is a nucleoside composed of hypoxanthine attached to 2′-deoxyribose via a β-N9-glycosidic bond. It is a DNA damage product resulting from the impairment of DNA by reactive nitrogen species. 2′-deoxyinsine can be used as a model compound to study the chemistry of adduct formation and radical chemistry that may affect DNA structures. 2′-Deoxyinosine is used to produce hybridization-sensitive fluorescent DNA probes with self-avoidance ability.

Ribitol

Ribitol (Adonitol) is a crystalline pentose alcohol formed by the reduction of ribose.

Glycodeoxycholic Acid

Glycodeoxycholic Acid is an endogenous metabolite. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis.

Glycolithocholic acid

Glycolithocholic acid, an endogenous metabolite, is a glycine conjugated secondary bile acid. Glycolithocholic acid can be used to study ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH0) and primary sclerosing cholangitis (PSC).

4-Aminohippuric Acid

4-Aminohippuric acid is a typical substrate of organic anion transport systems. 4-Aminohippuric acid is a diagnostic agent, useful in medical tests involving the kidney, used in the measurement of renal plasma flow.

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Keywords: trans-Aconitic acid , TAA supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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