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Trabectedin (Ecteinascidin 743; ET-743) is a tetrahydroisoquinoline alkaloid that binds to the minor groove of DNA, blocks stress-induced transcription of proteins, induces DNA backbone cleavage and apoptosis, and increases ROS production in MCF-7 and MDA-MB-453 cells. Trabectedin can be used in soft tissue sarcoma and ovarian cancer studies.
| Molecular Weight | 761.84 |
| Formula | C39H43N3O11S |
| CAS Number | 114899-77-3 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage | -20℃, protect from light, dry, sealed |
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