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TR-14035 is an orally active α4b7/a4b1 integrins (a4b7/a4b1 integrindual inhibitors, for α4b7 和 a4b1 function IC50 The values are 7 nM and 87 nM, respectively. TR-14035 can be used for the study of inflammatory and autoimmune diseases.
| Molecular Weight | 474.33 |
| Formula | C24H21Cl2NO5 |
| CAS Number | 232271-19-1 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Hao Li, et al. Expert Opin Ther Pat. α 4 β 7 integrin inhibitors: a patent review
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