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TP-6076 

Cat. No. M28619

All AbMole products are for research use only, cannot be used for human consumption.

TP-6076  Structure

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Quality Control & Documentation
Biological Activity

TP-6076 is a fully synthetic fluorocycline antibiotic, acts function via binding to the 30S ribosomal subunit and maintains its activity. TP-6076 displays potent mechanism-based antitranslational activity (Tet protein, IC50=0.18 μg/mL), shows a wide range of antimicrobial and antiparasitic activities.

Chemical Information
Molecular Weight 579.56
Formula C28H32F3N3O7
CAS Number 1575495-01-0
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Christopher E Morgan, et al. mBio. An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii

[2] Harald Seifert, et al. Int J Antimicrob Agents. In vitro activity of the novel fluorocycline TP-6076 against carbapenem-resistant Acinetobacter baumannii

[3] Osama Chahrour, et al. J Pharm Biomed Anal. Development and validation of an ICP-MS method for the determination of elemental impurities in TP-6076 active pharmaceutical ingredient (API) according to USP 〈232〉/〈233〉

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  Catalog
Abmole Inhibitor Catalog




Keywords: TP-6076  supplier, Antibiotic, inhibitors, activators

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